e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Palladium-catalyzed borylation of ortho-substituted phenyl halides and application to the one-pot synthesis of 2, 2'-disubstituted biphenyls

O Baudoin, D Guénard, F Guéritte

Index: Journal of Organic Chemistry, , vol. 65, # 26 p. 9268 - 9271

Full Text: HTML

Citation Number: 202

Abstract

... 2000, 41, 5853 and refs therein. (9) (a) Vaultier, M.; Carboni, B. In Comprehensive Organometallic Chemistry II; Abel, EW, Stone, FGA, Wilkinson, G., Eds.; Pergamon: Oxford, 1995; Vol. 11, p 191. ... Boc ) tert-butyloxycarbonyl, TES ) triethylsilyl. Notes J. Org. Chem., Vol. 65, No. ...

2-Methyl-2-propanyl (2-bromophenyl)carbamate Structure

2-Methyl-2-prop...

Pinacolborane Structure

~40%

N-BOC-aniline Structure

(2-boc-aminophenyl)boronic acid, pinacol ester Structure

(2-boc-aminophe...

2-Methyl-2-propanyl (2-iodophenyl)carbamate Structure

2-Methyl-2-prop...

Pinacolborane Structure

~55%

N-BOC-aniline Structure

(2-boc-aminophenyl)boronic acid, pinacol ester Structure

(2-boc-aminophe...

bromoanisole Structure

Pinacolborane Structure

~60%

Anisole Structure

2-(2-methoxyloxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Structure

2-(2-methoxylox...

2-Methyl-2-propanyl (2-bromophenyl)carbamate Structure

2-Methyl-2-prop...

Pinacolborane Structure

~56%

N-BOC-aniline Structure

(2-boc-aminophenyl)boronic acid, pinacol ester Structure

(2-boc-aminophe...

2-Methyl-2-propanyl (2-iodophenyl)carbamate Structure

2-Methyl-2-prop...

Pinacolborane Structure

~14%

N-BOC-aniline Structure

(2-boc-aminophenyl)boronic acid, pinacol ester Structure

(2-boc-aminophe...

2-Bromophenylacetonitrile Structure

2-Bromophenylac...

Pinacolborane Structure

~60%

Benzyl cyanide Structure

(2-CHLOROPHENYL)PHENYL-METHANONE Structure

(2-CHLOROPHENYL...

(2-Iodophenyl)acetonitrile Structure

(2-Iodophenyl)a...

Pinacolborane Structure

~91%

Benzyl cyanide Structure

(2-CHLOROPHENYL)PHENYL-METHANONE Structure

(2-CHLOROPHENYL...