. beta.-Lactams. XXXVI. Monocyclic cis. beta.-lactams via penams and cephams

AK Bose, MS Manhas, JS Chib…

Index: Bose,A.K. et al. Journal of Organic Chemistry, 1974 , vol. 39, # 19 p. 2877 - 2884

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Citation Number: 40

Abstract

susceptibility to electrophilic attack of the 5'-free dipyrrylmethanes was already described by us1 and later confirmed by other^.^ After 72 hr saponification was complete: nmr 2.7 (m, 8, CHzCHz), 3.5 (br, 4, CHzCO), 3.7 (br, 2, pyrr-CHppyrr), 4.0 (br, 2, CH2NH2). The substance was rapidly transformed into porphyrins by manipulation. Addition of an acid resin (IRC-H+ or IRA 120-H+) allowed adjustment of the solution to pH 7. This solution could be kept at- ...