A convenient and one??pot synthesis of 9??substituted carbazoles from primary amine hydrochlorides and 2, 5??dimethoxytetrahydrofuran

…, T Maruyama, K Harada, Y Omote

Index: Kashima, Choji; Hibi, Shigeki; Maruyama, Tatsuya; Harada, Kazuo; Omote, Yoshimori Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 913 - 916

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Citation Number: 21

Abstract

Abstract Carbazoles are the very important compounds in material science, nevertheless conventional syntheses required severe and complicated reaction conditions. In the process of preparation of pyrrole derivatives, we found that a primary amine hydrochloride 1 and 2, 5- dimethoxytetrahydrofuran 2 were refluxed in a benzenewater (100: 4 (v/v)) mixture to be obtained 9-substituted carbazole 5 in a high yield. This method is the one-pot synthesis of ...