Journal of Chemical Sciences

Microwave-assisted efficient synthesis of 2-arylbenzo [b] furans and 2-ferrocenylbenzo [b] furans from readily prepared propargylic alcohols and o-iodophenols

L Wu, X Shi, X Xu, F Liang, G Huang

Index: Wu, Liansheng; Shi, Xiaokang; Xu, Xiaoyun; Liang, Fen; Huang, Guosheng Journal of Chemical Sciences, 2011 , vol. 123, # 5 p. 697 - 702

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Citation Number: 2

Abstract

Abstract A simple, efficient and expeditious method for synthesis of 2-arylbenzo [b] furans and 2-ferrocenylbenzo [b] furans from readily prepared propargylic alcohols, o-iodophenols and silica gel with the catalyst of PdCl 2 (PPh 3) 2 (2 mol%)/CuI (2 mol%) and microwave- promoted Sonogashira coupling/cyclization reaction is developed. The methodology can produce good to excellent yields. In addition, this method can also be completed in one- ...