Synthesis

Hypervalent iodine mediated oxidative cyclization of O-hydroxystilbenes into benzo-and naphthofurans

FV Singh, T Wirth

Index: Singh, Fateh V.; Wirth, Thomas Synthesis, 2012 , vol. 44, # 8 p. 1171 - 1177

Full Text: HTML

Citation Number: 21

Abstract

Abstract A new and convenient metal-free cyclization of ortho-hydroxystilbenes into 2- arylbenzofurans and 2-arylnaphthofurans mediated by hypervalent iodine reagents is described. The cyclization products are isolated in good to excellent yields using stoichiometric (diacetoxyiodo) benzene in acetonitrile.

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2-Phenylbenzofuran Structure

1839-72-1

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phenylene-ethylene Structure

292638-84-7

phenylene-ethylene

iodophenol Structure

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iodophenol

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