e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Journal of the American Chemical Society
Synthesis of Alkyl and Substituted Alkyl Fluorides from p-Toluenesulfonic Acid Esters. The Preparation of p-Toluenesulfonic Acid Esters of Lower Alcohols1
WF Edgell, L Parts
Index: Edgell; Parts Journal of the American Chemical Society, 1955 , vol. 77, p. 4899,4901
A number of alkyl and substituted alkyl fluorides has been prepared from the corresponding p-toluenesulfonic acid esters (tosylates) by reaction with potassium fluoride. Isomerization, extensive elimination and doubling of chain length, the common disadvantages of the reaction between alkyl halides and transition metal fluorides, were not encountered. The method constitutes a convenient and dependable laboratory synthesis of primary and ...