Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl) piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl) amide, a high affinity TRPV1 (VR1 …

DM Swanson, AE Dubin, C Shah…

Index: Journal of Medicinal Chemistry, , vol. 48, # 6 p. 1857 - 1872

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Citation Number: 181

Abstract

... Journal of Medicinal Chemistry. ... effects observed for both TRPV1 agonists and antagonists, TRPV1 receptor ligands represent an important opportunity for the discovery of novel analgesic agents which has attracted the attention of several pharmaceutical companies and ...