Compilation of agmatine structure and imidazoline moiety leads to a new group of imidazoline/α2-adrenoceptor ligands, 4 (5)-(2-aminoethyl) imidazoline derivatives. In this study the exploration of previously unknown 4 (5)-(2-aminoethyl) imidazolines including the analogues of reported imidazoline and α2-aderenoceptors ligands: clonidine, rilmenidine, idazoxan, efaroxan, antazoline, tracizoline is described. The synthesis of a variety of novel ...
[Chapleo, Christopher B.; Myers, Peter L.; Butler, Richard C. M.; Davis, John A.; Doxey, John C.; et al. Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 570 - 576]
