Asymmetric alkylations using SuperQuat auxiliaries—an investigation into the synthesis and stability of enolates derived from 5, 5-disubstituted oxazolidin-2-ones

SD Bull, SG Davies, HJ Sanganee

Index: Bull, Steven D.; Davies, Stephen G.; Jones, Simon; Sanganee, Hitesh J. Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 4 p. 387 - 398

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Citation Number: 90

Abstract

Studies on the alkylation of enolates derived from a range of-acyl-5, 5-dimethyloxazolidin-2- ones and-acyl-5, 5-diphenyloxazolidin-2-ones reveal that high yields and high diastereoselectivities are best obtained when homochiral 4-isopropyl-5, 5- ...