General synthesis of. beta.,. gamma.-alkynylglycine derivatives

RM Williams, DJ Aldous, SC Aldous

Index: Williams, Robert M.; Aldous, David J.; Aldous, Suzanne C. Journal of Organic Chemistry, 1990 , vol. 55, # 15 p. 4657 - 4663

Full Text: HTML

Citation Number: 62

Abstract

The coupling of a-haloglycinates 8 with alkynyltin reagents produces the fully protected P, y- alkynylglycines 9. Subsequent deprotection of the amino or carboxyl groups generates differentially protected &y-alkynylglycine derivatives 10-14. The free amino acids were found to be too labile to isolate but can be generated in situ and trapped.

~73%

Lanthanide (III) Complexes That Contain a Self??Immolative A...

[Chauvin, Thomas; Torres, Susana; Rosseto, Renato; Kotek, Jan; Badet, Bernard; Durand, Philippe; Toth, Eva Chemistry - A European Journal, 2012 , vol. 18, # 5 p. 1408 - 1418]

2??Azabicyclo [2.2. 1] heptane??3??carboxylic acid??A bicycl...

[Gaitanopoulos, Dimitri E.; Weinstock, Joseph Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 957 - 959]

Synthesis of α-amino acids with β, γ-unsaturated side chains

[Castelhano, Arlindo L.; Horne, Stephen; Taylor, Gregg J.; Billedeau, Roland; Krantz, Allen Tetrahedron, 1988 , vol. 44, # 17 p. 5451 - 5466]