A novel fluorinated tryptamine with highly potent serotonin 5-HT 1A receptor agonist properties

…, D Kurrasch-Orbaugh, D Marona-Lewicka…

Index: Laban, Uros; Kurrasch-Orbaugh, Deborah; Marona-Lewicka, Danuta; E. Nichols, David Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 6 p. 793 - 795

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Citation Number: 9

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Synthesis and biological evaluation of a novel fluorinated tryptamine analogue are described. This new compound 1-(4-fluoro-5-methoxyindol-3-yl)pyrrolidine (2) was found to be a potent serotonin 5-HT 1A agonist. ... Synthesis and biological evaluation of a novel fluorinated tryptamine ...