Synthesis and antimicrobial activity of (E) stilbene derivatives

S Albert, R Horbach, HB Deising, B Siewert…

Index: Albert, Sabrina; Horbach, Ralf; Deising, Holger B.; Siewert, Bianka; Csuk, Rene Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 17 p. 5155 - 5166

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Citation Number: 28

Abstract

Abstract Plants use multiple defence mechanisms comprising both constitutive and inducible barriers to prevent entering of phytopathogenic micro-organisms. In many plant species one of the most efficient responses to combat attacking microbes is the rapid synthesis of antimicrobial low molecular weight phytoalexins, for example, resveratrol, 3, 5, 4′- trihydroxystilbene (1). Resveratrol and its natural derivatives, however, display only ...