Novel cross-linking alkylating agents, 1-(2-chloroethyl)-3-methyl-3-acyltriazenes

…, DL Shantz Jr, GN Chmurny, CJ Michejda

Index: Smith, Richard H.; Mehl, Andrew F.; Shantz, Donald L.; Chmurny, Gwendolyn N.; Michejda, Christopher J. Journal of Organic Chemistry, 1988 , vol. 53, # 7 p. 1467 - 1471

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Citation Number: 36

Abstract

The preparation and hydrolytic decomposition of a series of novel cross-linking alkylating agents, 142-chloroethyl)-3-methyl-3-acyltriazenea, is described. The syntheak of 3- carbethoxy-l-(2-chloroethyl)-3-methyltriazene, 3-acetyl-l-(2-chlorothyl)-3-methyltriazene, and l-(2-chloroethyl)-3-methyl-3-(methylcarbamoyl) triazene has been accomplished through the use of a common intermediate, l-(2-(tert-butyldimethylsiloxy) ethyl)-3-methyltri~ ene, ...