Journal of the American Chemical Society

A hybrid phosphorus ligand for highly enantioselective asymmetric hydroformylation

Y Yan, X Zhang

Index: Yan, Yongjun; Zhang, Xumu Journal of the American Chemical Society, 2006 , vol. 128, # 22 p. 7198 - 7202

Full Text: HTML

Citation Number: 147

Abstract

Today, hydroformylation is the largest industrially homogeneous catalytic process. Over 6 million tons of oxo products are being produced worldwide per year. Because chiral aldehydes can be easily converted into a variety of enantiomerically pure compounds, asymmetric hydroformylation 1 is potentially useful for the preparation of pharmaceutical products. Despite its importance, asymmetric hydroformylation is underdeveloped. Achieving high ee's (≥98% ee) remains ...

Highly enantioselective hydroformylation of olefins catalyze...

[Nozaki, Kyoko; Sakai, Nozomu; Nanno, Tetsuo; Higashijima, Takanori; Mano, Satoshi; Horiuchi, Toshihide; Takaya, Hidemasa Journal of the American Chemical Society, 1997 , vol. 119, # 19 p. 4413 - 4423]

Asymmetric hydroformylation catalyzed by homogeneous and pol...

[Parrinello, Giovanni; Stille, J. K. Journal of the American Chemical Society, 1987 , vol. 109, # 23 p. 7122 - 7127]

Synthesis of 2-arylpropionaldehydes through hydroformylation

[Neibecker, Denis; Reau, Regis; Lecolier, Serge Journal of Organic Chemistry, 1989 , vol. 54, # 22 p. 5208 - 5210]

Synthesis of Pt compounds containing chiral (2S, 4S)-pentane...

[Toth, Imre; Elsevier, Cornelis J.; De Vries, Johannes G.; Bakos, Jozsef; Smeets, Wilberth J. J.; Spek, Anthony L. Journal of Organometallic Chemistry, 1997 , vol. 540, # 1-2 p. 15 - 25]