Heteroaryl Hydroxycarbonylation: An Efficient, Robust, Practically Scalable Approach Using Formyl Acetate as the CO Source

AV Gadakh, D Chikanna, SS Rindhe…

Index: Gadakh, Amol V.; Chikanna, Dinesh; Rindhe, Sahebrao S.; Karale, Bhausaheb K. Synthetic Communications, 2012 , vol. 42, # 5 p. 658 - 666

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Citation Number: 4

Abstract

From an industrial point of view, the carbonylation of hetero aryl halides [ 1 1. (a) Albaneze-Walker , J. ; Murry , JA ; Soheili , A. ; Ceglia , S. ; Springfield , SA ; Bazaral , C. ; Dormer , PG ; Hughes , DL Practical application of new catalytic methods: A concise synthesis of a potent PDE IV inhibitor . Tetrahedron 2005 , 61 , 6330 – 6336 ; (b) El-ghayoury , A. ; Ziessel , R. Facile synthesis of polypyridine esters: A route to functionalized aldehydes . J. Org. Chem. 2000 , 65 , 7757 – 7763 ; (c) ...