Arene–Metal π-Complexation as a Traceless Reactivity Enhancer for C–H Arylation

…, K Krämer, XC Cambeiro, I Larrosa

Index: Ricci, Paolo; Kraemer, Katrina; Cambeiro, Xacobe C.; Larrosa, Igor Journal of the American Chemical Society, 2013 , vol. 135, # 36 p. 13258 - 13261

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Citation Number: 27

Abstract

Current approaches to facilitate C–H arylation of arenes involve the use of either strongly electron-withdrawing substituents or directing groups. Both approaches require structural modification of the arene, limiting their generality. We present a new approach where C–H arylation is made possible without altering the connectivity of the arene via π-complexation of a Cr (CO) 3 unit, greatly enhancing the reactivity of the aromatic C–H bonds. We apply ...