Asymmetric phase-transfer catalyzed glycolate alkylation, investigation of the scope, and application to the synthesis of (-)-ragaglitazar

MB Andrus, EJ Hicken, JC Stephens…

Index: Journal of Organic Chemistry, , vol. 70, # 23 p. 9470 - 9479

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Citation Number: 40

Abstract

... The Journal of Organic Chemistry. ... 84602-5700. J. Org. Chem. , 2005 ... new substrate. The key effect is the formation of the organic soluble glycolate enolate-cinchonidinium tight ion-pair 12 that selectively reacts with electrophiles. 1a ...

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