Synthesis of novel isoxazole-benzoquinone hybrids via 1, 3-dipolar cycloaddition reaction as key step

…, M Behera, K Raghavulu, AJ Shree, S Yennam

Index: Ravi Kumar; Behera, Manoranjan; Raghavulu; Jaya Shree; Yennam, Satyanarayana Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4108 - 4113

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Citation Number: 10

Abstract

An efficient method for the preparation of novel 2-(5-arylisoxazol-3-yl) cyclohexa-2, 5-diene- 1, 4-dione hybrids via 1, 3-dipolar cycloaddition followed by an oxidation reaction using ceric ammonium nitrate (CAN) has been described. Using this method, various aryl as well as alkyl substituted isoxazole-benzoquinone hybrids were synthesized in high yields.