Tetrahedron Letters

Total synthesis of the fungal metabolite (±)-acremine G: acceleration of a biomimetic Diels–Alder reaction on silica gel

G Mehta, TB Khan, YCS Kumar

Index: Mehta, Goverdhan; Khan, Tabrez Babu; Sunil Kumar Tetrahedron Letters, 2010 , vol. 51, # 39 p. 5116 - 5119

Full Text: HTML

Citation Number: 4

Abstract

Endophytic fungi, as they grow on their plant hosts, continually interacting and exchanging evolutionary memories, produce a wide range of novel and interesting secondary metabolites. 1 In particular, fungal metabolites of the genus Acremonium have proved to be a rich repository of diverse natural products, endowed with broad-ranging biological activity, encompassing immunosuppressant cyclosporins to tremorgenic indoles. 2 A research group 3 in Italy has explored a strain of ...