Abstract 3-Methyl-1H-quinoxalin-2-one has been doubly lithiated with n-butylithium at-78 C in THF. The dilithio reagent thus obtained reacts with various electrophiles (iodomethane, iodoethane, D 2 O, benzaldehyde, benzophenone, cyclohexanone) to give modified 3- substituted 1H-quinoxalin-2-ones in good yields. In the reaction of the dilithio reagent with phenyl isothiocyanate the product was a tautomer of the simple substitution product. ...
