Tetrahedron Letters

nBu 4 NI-catalyzed oxidative amidation of aldehydes with tertiary amines

S Wang, J Wang, R Guo, G Wang, SY Chen, XQ Yu

Index: Wang, Shan; Wang, Jian; Guo, Rui; Wang, Gao; Chen, Shan-Yong; Yu, Xiao-Qi Tetrahedron Letters, 2013 , vol. 54, # 46 p. 6233 - 6236

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Citation Number: 12

Abstract

Amide functionalities are among the most important motifs in natural products, polymers, agrochemicals, and pharmaceuticals. 1 Acylation of amines with activated carboxylic acid derivatives is a common strategy. 1 and 2 However, due to the lability of activated carboxylic acid derivatives, novel chemical approaches to amide formation are therefore being developed. Examples include the metal-catalyzed aminocarbonylation, 3 modified Staudinger reaction, 4 acid- ...