Canadian journal of chemistry

Preparation of α-aminothioamides from aldehydes

M Paventi, JT Edward

Index: Paventi, Martino; Edward, John T. Canadian Journal of Chemistry, 1987 , vol. 65, p. 282 - 289

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Citation Number: 19

Abstract

The conversion of aldehydes into α-aminonitriles and thence into imidazolidin-4-thiones has been studied. Hydrolysis of the appropriate imidazolidin-4-thiones gave thioamides of nine naturally occurring α-amino acids. The possible pre-biotic significance of these compounds is discussed.

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Novel N-chloroheterocyclic antimicrobials

[Francavilla, Charles; Turtle, Eric D.; Kim, Bum; O'Mahony, Donogh J.R.; Shiau, Timothy P.; Low, Eddy; Alvarez, Nichole J.; Celeri, Chris E.; D'Lima, Louisa; Friedman, Lisa C.; Ruado, Francis S.; Xu, Ping; Zuck, Meghan E.; Anderson, Mark B.; Najafi, Ramin; Jain, Rakesh K. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 10 p. 3029 - 3033]