Canadian journal of chemistry

Preparation of α-aminothioamides from aldehydes

M Paventi, JT Edward

Index: Paventi, Martino; Edward, John T. Canadian Journal of Chemistry, 1987 , vol. 65, p. 282 - 289

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Citation Number: 19

Abstract

The conversion of aldehydes into α-aminonitriles and thence into imidazolidin-4-thiones has been studied. Hydrolysis of the appropriate imidazolidin-4-thiones gave thioamides of nine naturally occurring α-amino acids. The possible pre-biotic significance of these compounds is discussed.