Glycopeptide Synthesis Using O??Pentafluorophenyluronium Salts as novel condensing reagents

J Habermann, H Kunz

Index: Habermann, Joerg; Kunz, Horst Journal fur Praktische Chemie - Chemiker - Zeitung, 1998 , vol. 340, # 3 p. 233 - 239

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Citation Number: 26

Abstract

Abstract. Pentafluorophenyluronium salts and related cou- pling reagents for the solid-phase synthesis of peptides and glycopeptides have been developed and employed in the ... In the field of peptide synthesis pentafluorophenyl es- ters of amino acids have been reported to be very effi- cient [ 11 in amide bond formation. Methods based on in situ formation of these activated carboxylic compounds have not been described so far. We report here on the synthesis ...