Tetrahedron

Group 3 metal (Sc, La) triflates as catalysts for the carbomethoxylation of aliphatic amines with dimethylcarbonate under mild conditions

M Distaso, E Quaranta

Index: Distaso, Monica; Quaranta, Eugenio Tetrahedron, 2004 , vol. 60, # 7 p. 1531 - 1539

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Citation Number: 37

Abstract

The activity of Sc (OTf) 3 and La (OTf) 3 (OTf= SO3CF3) as catalysts for the phosgene-free synthesis of carbamate esters via carbomethoxylation of aliphatic amines with dimethylcarbonate (DMC) has been investigated. In the presence of M (OTf) 3 (M= Sc, La), primary and secondary aliphatic amines easily react with dimethylcarbonate, under very mild conditions (20° C), to afford carbamate esters with good yield and excellent selectivity ...