Comptes Rendus Chimie

Squaric acid as an impressive organocatalyst for Michael addition in water

N Azizi, E Saki, M Edrisi

Index: Azizi, Najmadin; Saki, Elham; Edrisi, Mahtab Comptes Rendus Chimie, 2011 , vol. 14, # 11 p. 973 - 977

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Citation Number: 13

Abstract

A simple, green, and environmentally benign protocol for squaric acid (5mg) catalyst conjugate addition of aromatic amines and thiols to unsaturated carbonyl compounds in water in good to excellent yields is developed. The advantages of low sensitivity toward moisture and oxygen, high tolerance of different functional groups, green reaction media and efficient recyclability make this organocatalyst suitable for both laboratory and ...