Tetrahedron letters

Multifunctional catalysis of a ruthenium-grafted hydrotalcite: one-pot synthesis of quinolines from 2-aminobenzyl alcohol and various carbonyl compounds via aerobic …

K Motokura, T Mizugaki, K Ebitani, K Kaneda

Index: Motokura, Ken; Mizugaki, Tomoo; Ebitani, Kohki; Kaneda, Kiyotomi Tetrahedron Letters, 2004 , vol. 45, # 31 p. 6029 - 6032

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Citation Number: 90

Abstract

The Ru-grafted hydrotalcite was found to be an excellent multifunctional catalyst for one-pot synthesis of quinolines from 2-aminobenzyl alcohol and various carbonyl compounds. These quinolines were obtained through aerobic oxidation by the Ru species, followed by aldol reaction on base sites of the hydrotalcite.