Rhodium (II)-and copper (I)-catalyzed intramolecular carbon-hydrogen bond insertions with metal carbenoids derived from diazo ketones

P Müller, E Maîtrejean

Index: Mueller, Paul; Maitrejean, Esther Collection of Czechoslovak Chemical Communications, 1999 , vol. 64, # 11 p. 1807 - 1826

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Citation Number: 25

Abstract

Abstract The decomposition of diazo ketones in the presence of Rh (II) and Cu (I) catalysts affords products of CH bond insertion in high yields. The effect of structural variation on intramolecular and transannular CH insertions of diazo ketones has been investigated. The enantioselectivity of the insertion was examined with 15 chiral catalysts of different structural types. It was low in all cases. The poor enantioselectivity of the insertion of diazo ketones ...