Tetrahedron Letters

Weinreb amide based building blocks for convenient access to 1, 1-diarylethenes and isocombretastatin analogues

S Balasubramaniam, H Kommidi, IS Aidhen

Index: Balasubramaniam, Sivaraman; Kommidi, Harikrishna; Aidhen, Indrapal Singh Tetrahedron Letters, 2011 , vol. 52, # 21 p. 2683 - 2686

Full Text: HTML

Citation Number: 5

Abstract

Abstract A successful strategy based on the synthetic equivalent containing Weinreb amide functionality for the convenient access to 1, 1-diarylethenes in general and for the isocombretastatin analogues in particular has been developed from the commercially available glyoxalic acid. The convenience with which the structural variations can be made in assembling the aryl residues shows generality associated with the developed strategy. ...