Synthesis of Substituted Furoates from Acrylates and Aldehydes by Pd (OAc) 2/HPMoV/CeCl3/O2 System

…, Y Hatamoto, Y Obora, S Sakaguchi…

Index: Tamaso, Ken-Ichi; Hatamoto, Yuji; Obora, Yasushi; Sakaguchi, Satoshi; Ishii, Yasutaka Journal of Organic Chemistry, 2007 , vol. 72, # 23 p. 8820 - 8823

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Citation Number: 10

Abstract

A new synthetic method of substituted furoates from acrylates and aldehydes was developed by Pd (OAc) 2 combined with molybdovanadophosphoric acid and Lewis acid under atmospheric dioxygen. The reaction was found to proceed through the palladium-catalyzed acetalization of acrylates with methanol followed by the reaction of the resulting acetals with aldehydes.