Microwave accelerated synthesis of isoxazole hydrazide inhibitors of the system xc-transporter: Initial homology model

…, J Mirzaei, J Rudolph, SA Smith, JL Newell…

Index: Matti, Afnan A.; Mirzaei, Joseph; Rudolph, John; Smith, Stephen A.; Newell, Jayme L.; Patel, Sarjubhai A.; Braden, Michael R.; Bridges, Richard J.; Natale, Nicholas R. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 21 p. 5931 - 5935

Full Text: HTML

Citation Number: 2

Abstract

Abstract Microwave accelerated reaction system (MARS) technology provided a good method to obtain selective and open isoxazole ligands that bind to and inhibit the Sx c-Sx c- antiporter. The MARS provided numerous advantages, including: shorter time, better yield ...