Synthesis of [14C] KT3??671, 2??Propyl??8??oxo??1??[(2′??(1H??[14C] tetrazole??5??yl) biphenyl??4??yl) methyl]??4, 5, 6, 7??tetrahydro??cycloheptimidazole, a novel potent …

N Ueyama, T Yanagisawa…

Index: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 36, # 10 p. 915 - 919

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Abstract

Journal of Labelled Conipounds and Rodiopharrnaceuticals-Vol. ... which has been found to be a potent and selective angiotesin Il receptor antagonist, was synthesized in I4C-labelled form by ... HMPA), K,CO, and KI at 130- 140°C for 3h afforded the key labeled compound 5 in a ...