Abstract 2-Propyl-8-oxo-1-[(2′-(1H-tetrazole-5-yl) biphenyl-4-yl) methyl]-4, 5, 6, 7- tetrahydrocyclohept imidazole (KT3-671), which has been found to be a potent and selective angiotesin II receptor antagonist, was synthesized in 14 C-labelled form by using potassium [14 C]-cyanide.[14 C](KT3-671) 9 with a specific activity of 1.74 GBq/mmol was prepared in four steps in 29.8% overall radio-chemical yield from potassium [14 C]-cyanide.
