Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases

Z Xia, C Knaak, J Ma, ZM Beharry…

Index: Wada, Akimori; Kanatomo, Shoichi; Nagai, Sotoo Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1016 - 1022

Full Text: HTML

Citation Number: 135

Abstract

... Journal of Medicinal Chemistry. ... 86. DOI: 10.1021/jm800937p. Publication Date (Web): December 15, 2008. Copyright © 2008 American Chemical Society. ... Department of Pharmaceutical and Biomedical Sciences, South Carolina College of Pharmacy, University of South Carolina ...

 Related Synthetic Route
Phenol Structure

108-95-2

Phenol

~%

(3-CARBOXY-5-FLUORO)BENZENEBORONIC ACID Structure

15182-06-6

(3-CARBOXY-5-FL...

N,N-Dimethyl-2-phenoxyethanamine Structure

13468-02-5

N,N-Dimethyl-2-...

N,N-Dimethylformamide Structure

68-12-2

N,N-Dimethylfor...

~%

(3-CARBOXY-5-FLUORO)BENZENEBORONIC ACID Structure

15182-06-6

(3-CARBOXY-5-FL...

1-Bromo-2-methoxyethane Structure

6482-24-2

1-Bromo-2-metho...

Phenol Structure

108-95-2

Phenol

~37%

Benzene, (2-methoxyethoxy)- Structure

41532-81-4

Benzene, (2-met...

Phenol Structure

108-95-2

Phenol

~%

2-(2-methoxyethoxy)benzaldehyde Structure

92637-96-2

2-(2-methoxyeth...

Benzene, (2-methoxyethoxy)- Structure

41532-81-4

Benzene, (2-met...

N,N-Dimethylformamide Structure

68-12-2

N,N-Dimethylfor...

~%

2-(2-methoxyethoxy)benzaldehyde Structure

92637-96-2

2-(2-methoxyeth...

Phenol Structure

108-95-2

Phenol

~%

2-(2-Methoxyethoxy)benzoic acid Structure

98684-32-3

2-(2-Methoxyeth...

Carbon dioxide Structure

124-38-9

Carbon dioxide

Benzene, (2-methoxyethoxy)- Structure

41532-81-4

Benzene, (2-met...

~%

2-(2-Methoxyethoxy)benzoic acid Structure

98684-32-3

2-(2-Methoxyeth...

2-Bromo-N,N-dimethylethanamine hydrobromide Structure

2862-39-7

2-Bromo-N,N-dim...

Phenol Structure

108-95-2

Phenol

~75%

N,N-Dimethyl-2-phenoxyethanamine Structure

13468-02-5

N,N-Dimethyl-2-...


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