It is well known that thiazole derivatives are important compounds in medicinal chemistry 1 due to their broad range of biological activities. This type of heterocycles have shown a wide variety of pharmacoactive properties as anti-inflammatory, 2 anti-tubercular, 3 anti-bacterial, 4 fungicidal, 5 local anaesthetic, 6 tranquilizers, 7 insecticidal, 8 anti-microbial, 9 anti-tumor 10 and diuretic. 11 Considerable efforts have been devoted to the synthesis of this type of ...
