e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Unexpected behavior of the reaction between 1, 2-diaza-1, 3-butadienes and 3-dimethylaminopropenoates: A useful entry to new pyrrolines, pyrroles, and oxazolines
…, A Golobic, B Stanovnik, J Svete
Index: Stanovnik, Branko; Svete, Jurij; Tisler, Miha; Zorz, Lilijana; Hvala, Ales; Simonic, Igor Heterocycles, 1988 , vol. 27, # 4 p. 903 - 910
We observed a nucleophilic attack by the ene-amino carbon of 3- dimethylaminopropenoates at the terminal carbon of the azo-ene system of 1, 2-diaza-1, 3- butadienes. In tetrahydrofuran at 65° C, this attack produced 1-aminopyrrolines with a high