The Journal of Organic Chemistry

A new procedure for regiospecific syntheses of benzopyran-1-ones

FM Hauser, VM Baghdanov

Index: Hauser, Frank M.; Baghdanov, Vaceli M. Journal of Organic Chemistry, 1988 , vol. 53, # 20 p. 4676 - 4681

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Citation Number: 41

Abstract

A new, general route to benzopyran-1-ones 33 from phthalaldehydic acids 27 and nitroalkanes 28 is described. The sequence permits straightforward variation of both the 3- substituent and the pattern of functionalization on the aromatic ring of the benzopyran ring system. The (nitroalky1) isobenzofuranones 29 obtained from condensation of 27 and 28 with triethylamine in DMSO were converted to 2-(2-nitroalkyl) benzoic acids 30 with ...