Modular access to heterocycles: methyl 3-aminobenzo [b] thiophene-2-carboxylate–thiourea linkage or pyrimidine-4-one-2-thione formation

…, A Šačkus, A Tatibouët, P Rollin

Index: Rousseau, Jolanta; Krisciuniene, Vilija; Rimkeviciute, Ilona; Rousseau, Cyril; Amankaviciene, Virgine; Sackus, Algirdas; Tatibouet, Arnaud; Rollin, Patrick Monatshefte fur Chemie, 2009 , vol. 140, # 3 p. 339 - 348

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Citation Number: 5

Abstract

Abstract Modular conditions for the formation of thioureas or pyrimidine-4-one-2-thiones connected to the benzo [b] thiophene, benzene and indole structures were performed. A benzo [b] thiophene isothiocyanate derivative was used as a model to study the condensation with simple aromatic amines and amino-l-sorbose derivative. The construction of pyrimidine-4-one-2-thiones using basic conditions afforded efficiently new heterocyclic ...