One??pot synthesis of quinazoline??2, 4 (1H, 3H)??diones and 2??thioxoquinazolinones with the aid of low??valent titanium reagent

GL Dou, MM Wang, ZB Huang…

Index: Dou, Guo-Lan; Wang, Man-Man; Huang, Zhi-Bin; Shi, Da-Qing Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 4 p. 645 - 649

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Citation Number: 12

Abstract

It has been reported that quinazolinones show antihypertonic, antirheumatic, antianaphylactic, antiasthmatic, tranquilizing, neuro-stimulating, and benzodiazepine binding activity [1, 2]. The quinazolindione moiety, in particular, is widely found in natural