Regio-and Stereospecific Syntheses of syn-and anti-1, 2-Imidazolylpropylamines from the Reaction of 1, 1'-Carbonyldiimidazole with syn-and anti-1, 2-Amino Alcohols

MJ Mulvihill, C Cesario, V Smith, P Beck…

Index: Mulvihill, Mark J.; Cesario, Cara; Smith, Vanessa; Beck, Patricia; Nigro, Anthony Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 5124 - 5127

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Citation Number: 22

Abstract

The regio-and stereospecific conversion of syn-and anti-1, 2-amino alcohols to their respective syn-and anti-1, 2-imidazolylpropylamines via treatment with 1, 1'- carbonyldiimidazole is described. The rationale behind the regio-and stereospecific nature as well as the generality of the reaction is discussed.