Organic letters

Three-component reaction between alkynes, elemental sulfur, and aliphatic amines: a general, straightforward, and atom economical approach to thioamides

…, MQ Tran, L Ermolenko, A Al-Mourabit

Index: Nguyen, Thanh Binh; Ermolenko, Ludmila; Al-Mourabit, Ali Organic Letters, 2013 , vol. 15, # 16 p. 4218 - 4221

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Citation Number: 31

Abstract

Although a wide range of preparative methods of thioamides have been developed, there is an ongoing search for new methods which should (1) be operationally simple, (2) be based on an atom-, step-, and redox-economical transformations, (3) use readily available and inexpensive starting materials, and (4) tolerate a wide range of functional groups that are generally incompatible with Lawesson's reagent and other known reaction conditions. As a consequence of our ...