Synthesis

Macrocycles by ring-closing metathesis

A Fürstner, K Langemann

Index: Fuerstner, Alois; Langemann, Klaus Synthesis, 1997 , # 7 p. 792 - 803

Full Text: HTML

Citation Number: 180

Abstract

In contrast, the relevance of RCM for the formation of medium and large rings has been perceived only recently. Thus, it has been shown that RCM very well applies to substrates devoid of any conformational constraints and must be considered to be among the most efficient entries into macrocycles provided that the site of ring-closure is properly chosen.“6 These preliminary results together with some very recent applications of RCM to the syn- ...