Synthesis of disulfides by laccase-catalyzed oxidative coupling of heterocyclic thiols

HT Abdel-Mohsen, K Sudheendran, J Conrad…

Index: Abdel-Mohsen, Heba T.; Sudheendran, Kavitha; Conrad, Juergen; Beifuss, Uwe Green Chemistry, 2013 , vol. 15, # 6 p. 1490 - 1495

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Citation Number: 18

Abstract

Disulfides play a vital role in living systems with respect to the folding, stability and activity of numerous proteins 11 as well as their DNA-cleaving properties. 12 They are also of great interest as cleavable linkages for the design of drug delivery systems. 13 In organic chemistry, disulfides are used as intermediates for the synthesis of sulfinyl and sulfenyl compounds. 14 In industry, they are of great importance as vulcanizing agents. 15 In addition, it is known ...