Two classes of fused nitrogen heterocycles were designed as CK2 inhibitor candidates on the basis of previous structure–activity relationship (SAR) studies. Various dipyrrolo [3, 2-b: 2′, 3′-e] pyridine and benzo [g] indazole derivatives were prepared using transition-metal- catalysed cascade and/or multicomponent reactions. Biological evaluation of these candidates revealed that benzo [g] indazole is a promising scaffold for potent CK2 ...
