Aminopyridazines as acetylcholinesterase inhibitors

JM Contreras, YM Rival, S Chayer…

Index: Journal of Medicinal Chemistry, , vol. 42, # 4 p. 730 - 741

Full Text: HTML

Citation Number: 144

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. A general synthesis of 3-aminoalkyl- substituted pyridazines 13-15 (Tables 2 and 4) is shown in Scheme 1. The key intermediates in their preparation are imino chlorides 2 ...

 Related Synthetic Route
Piperidine-4-carboxamide Structure

39546-32-2

Piperidine-4-ca...

~%

(1-Benzyl-4-piperidinyl)methylamine Structure

88915-26-8

(1-Benzyl-4-pip...

N/A Structure

221196-22-1

N/A

~%

N1-BENZYL-N1-METHYLPROPANE-1,3-DIAMINE Structure

13910-49-1

N1-BENZYL-N1-ME...

N-[4-(benzyl-methyl-amino)-butyl]-phthalimide Structure

6820-99-1

N-[4-(benzyl-me...

~%

N-BENZYL-N-METHYLPUTRESCINE Structure

221196-25-4

N-BENZYL-N-METH...

N-Methylbenzylamine Structure

103-67-3

N-Methylbenzylamine

~%

N-BENZYL-N-METHYLPUTRESCINE Structure

221196-25-4

N-BENZYL-N-METH...

2-(1-Benzylpiperidin-4-ylidene)acetonitrile Structure

55022-82-7

2-(1-Benzylpipe...

~%

4-(2-Aminoethyl)-1-benzylpiperidine Structure

86945-25-7

4-(2-Aminoethyl...

1,2,3,4-Tetrahydroisoquinoline Structure

91-21-4

1,2,3,4-Tetrahy...

~%

2(1H)-Isoquinolineethanamine,3,4-dihydro- Structure

53356-51-7

2(1H)-Isoquinol...

5-Phenylpyrimidin-2(1H)-one Structure

56863-46-8

5-Phenylpyrimid...

~%

2-Chloro-5-phenylpyrimidine Structure

22536-62-5

2-Chloro-5-phen...


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