Tetrahedron letters

Photochemical halogen-exchange reaction of 5-iodouracil-containing oligonucleotides

K Kawai, I Saito, H Sugiyama

Index: Kawai, Kiyohiko; Saito, Isao; Sugiyama, Hiroshi Tetrahedron Letters, 1999 , vol. 40, # 31 p. 5721 - 5724

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Citation Number: 6

Abstract

Photoreactions of 5-iododeoxyuridine (dIU) and dIU-containing oligonucleotides in aqueous solutions in the presence of various inorganic salts have been investigated. In the presence of NaCl and NaBr, dIU and dIU-containing oligonucleotides undergo an efficient photochemical halogen-exchange reaction to give dCIU and dBrU, respectively.

~19%

~28%

Synthesis and properties of DNA containing cyclonucleosides

[Yueh, Han; Yu, Hongchuan; Theile, Christopher S.; Pal, Ayan; Horhota, Allen; Greco, Nicholas; Christianson, Carl V.; McLaughlin, Larry W. Nucleosides, Nucleotides and Nucleic Acids, 2012 , vol. 31, # 9 p. 661 - 679]