A convenient method for the N-formylation of amines at room temperature using TiO 2-P25 or sulfated titania

B Krishnakumar, M Swaminathan

Index: Krishnakumar; Swaminathan Journal of Molecular Catalysis A: Chemical, 2011 , vol. 334, # 1-2 p. 98 - 102

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Citation Number: 55

Abstract

Semiconductor catalyzed N-formylation of a variety of amines using formic acid as formylating agent has been investigated. Primary and secondary amines were found to react efficiently with formic acid in the presence of TiO2-P25 or sulfated titania giving N-formyl derivatives in high yields at room temperature. Sulfated titania is found to be more efficient and reusable than TiO2-P25 for N-formylation of amines.

~98%

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