Tetrahedron

Synthesis of π-conjugated thiophenes starting from substituted 3-oxopropanenitriles via Gewald reaction

Z Puterová, A Andicsová, D Végh

Index: Puterova, Zita; Andicsova, Anita; Vegh, Daniel Tetrahedron, 2008 , vol. 64, # 49 p. 11262 - 11269

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Citation Number: 42

Abstract

This paper describes the synthesis of β-aryl and β-heteroaryl substituted 2-aminothiophenes as a novel class of building blocks in oligo-and polythiophenes. The synthesis was carried out in two steps, involving synthesis of substituted 3-oxopropanenitrile intermediates, followed by the Gewald reaction.