Umpolung Strategy for Synthesis of β-Ketonitriles through Hypervalent Iodine-Promoted Cyanation of Silyl Enol Ethers

…, J Li, Q Liu, J Pan, R Huang, Y Xiong

Index: Akula, Ramulu; Xiong, Yan; Ibrahim, Hasim RSC Advances, 2013 , vol. 3, # 27 p. 10731 - 10735

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Citation Number: 13

Abstract

An efficient method to synthesize β-ketonitriles from silyl enol ethers by an umploung hypervalent iodine (III)–CN species generated in situ from PhIO/BF3· Et2O/TMSCN has been developed for the first time. This method can be applied to structurally diverse aromatic and