Tetrahedron letters

Suzuki–Miyaura cross-coupling of aryl and alkyl halides using palladium/imidazolium salt protocols

…, S Caddick, FGN Cloke, AP Herring, PB Hitchcock

Index: Arentsen, Katherine; Caddick, Stephen; Cloke, F. Geoffrey N.; Herring, Adam P.; Hitchcock, Peter B. Tetrahedron Letters, 2004 , vol. 45, # 17 p. 3511 - 3515

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Citation Number: 131

Abstract

A simple new protocol for the high yielding Suzuki–Miyaura cross-couplings of aryl chlorides with aryl boronic acids using a palladium/imidazolium salt catalytic system is presented. The first examples of a palladium/imidazolium salt protocol for sp3–sp3 Suzuki–Miyaura couplings of alkyl halides are also disclosed.