e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Homogeneous Catalytic Hydrogenation of Amides to Amines

J Coetzee, DL Dodds, J Klankermayer…

Index: Chemistry - A European Journal, , vol. 19, # 33 p. 11039 - 11050

Full Text: HTML

Citation Number: 1

Abstract

... Explore this journal >. Chemistry – A European Journal: Previous article in issue: Acid–Base-Controlled Stereoselective Metalation of ... benign amide hydrogenation reactions are rare and for this reason the American Chemical Society Green Chemistry Institute (GCI) and ...

3'-Methylacetanilide Structure

3'-Methylacetanilide

~%

PYRROLIDINE, 1-(3-METHYLPHENYL)- Structure

PYRROLIDINE, 1-...

3-Toluidine Structure

N-Ethyl-3-methylaniline Structure

N-Ethyl-3-methy...

Detail

O-ACETOTOLUIDIDE Structure

O-ACETOTOLUIDIDE

~%

n,n-diethyl-o-toluidine Structure

n,n-diethyl-o-t...

2-Ethylaminotoluene Structure

2-Ethylaminotoluene

o-Toluidine Structure

1N1&VR Structure

~%

dimethylbenzylamine Structure

dimethylbenzylamine

dibemethine Structure

Tribenzylamine Structure

Detail

Benzenecarboximidic acid, N-methyl- (9CI) Structure

Benzenecarboxim...

~%

dimethylbenzylamine Structure

dimethylbenzylamine

dibemethine Structure

Tribenzylamine Structure

Detail

1N1&VR Structure

~%

dimethylbenzylamine Structure

dimethylbenzylamine

dibemethine Structure

Tribenzylamine Structure

Detail

n-benzylacetamide Structure

n-benzylacetamide

~%

N-ethyldibenzylamine Structure

N-ethyldibenzylamine

benzyldiethylamine Structure

benzyldiethylamine

Tribenzylamine Structure

Detail

Benzenecarboximidic acid, N-methyl- (9CI) Structure

Benzenecarboxim...

~%

dimethylbenzylamine Structure

dimethylbenzylamine

dibemethine Structure

Tribenzylamine Structure

Detail

Benzylamine Structure

~%

N-ethyldibenzylamine Structure

N-ethyldibenzylamine

Tribenzylamine Structure

N-Ethylbenzylamine Structure

N-Ethylbenzylamine

Detail

p-toluoyl chloride Structure

p-toluoyl chloride

Benzylamine Structure

~%

N/A Structure

Tribenzylamine Structure

Detail

Acetanilide Structure

~%

N-Ethylaniline Structure

N,N-Diethylaniline Structure

N,N-Diethylaniline

Acetanilide Structure

~%

Ethanol Structure

N-Ethylaniline Structure

N,N-Diethylaniline Structure

N,N-Diethylaniline

Acetanilide Structure

~%

N-Ethylaniline Structure

Structure

N,N-Diethylaniline Structure

N,N-Diethylaniline

4-Chloroacetanilide Structure

4-Chloroacetanilide

~%

N-(4-chlorophenyl)-N,N-diethylamine Structure

N-(4-chlorophen...

N-(4-chlorophenyl)-N-ethylacetamide Structure

N-(4-chlorophen...

4-Chloroaniline Structure

4-Chloroaniline

Detail

3'-Methylacetanilide Structure

3'-Methylacetanilide

~%

PYRROLIDINE, 1-(3-METHYLPHENYL)- Structure

PYRROLIDINE, 1-...

3-Toluidine Structure

N-Ethyl-3-methylaniline Structure

N-Ethyl-3-methy...

Detail

Benzenecarboximidic acid, N-methyl- (9CI) Structure

Benzenecarboxim...

~%

dimethylbenzylamine Structure

dimethylbenzylamine

dibemethine Structure

Tribenzylamine Structure

Detail

4'-Methylacetanilide Structure

4'-Methylacetanilide

~%

PYRROLIDINE, 1-(4-METHYLPHENYL)- Structure

PYRROLIDINE, 1-...

n,n-diethyl-p-toluidine Structure

n,n-diethyl-p-t...

p-Toluidine Structure

Detail

4-Chloroacetanilide Structure

4-Chloroacetanilide

~%

N-(4-chlorophenyl)-N,N-diethylamine Structure

N-(4-chlorophen...

N-(4-chlorophenyl)-N-ethylacetamide Structure

N-(4-chlorophen...

4-Chloroaniline Structure

4-Chloroaniline

Detail

Acetamide,N-(3-chlorophenyl)- Structure

Acetamide,N-(3-...

~%

(3-Chlorophenyl)ethylamine Structure

(3-Chlorophenyl...

3-chloro-N,N-diethylaniline Structure

3-chloro-N,N-di...

3-Chloroaniline Structure

3-Chloroaniline

O-ACETOTOLUIDIDE Structure

O-ACETOTOLUIDIDE

~%

n,n-diethyl-o-toluidine Structure

n,n-diethyl-o-t...

2-Ethylaminotoluene Structure

2-Ethylaminotoluene

o-Toluidine Structure

n-benzylacetamide Structure

n-benzylacetamide

~%

N-ethyldibenzylamine Structure

N-ethyldibenzylamine

benzyldiethylamine Structure

benzyldiethylamine

Tribenzylamine Structure

Detail

Benzenecarboximidic acid, N-methyl- (9CI) Structure

Benzenecarboxim...

~%

dimethylbenzylamine Structure

dimethylbenzylamine

dibemethine Structure

Tribenzylamine Structure

Detail

Benzylamine Structure

~%

N-ethyldibenzylamine Structure

N-ethyldibenzylamine

Tribenzylamine Structure

N-Ethylbenzylamine Structure

N-Ethylbenzylamine

Detail

p-toluoyl chloride Structure

p-toluoyl chloride

Benzylamine Structure

~%

N/A Structure

Tribenzylamine Structure

Detail

4'-Methylacetanilide Structure

4'-Methylacetanilide

~%

PYRROLIDINE, 1-(4-METHYLPHENYL)- Structure

PYRROLIDINE, 1-...

n,n-diethyl-p-toluidine Structure

n,n-diethyl-p-t...

p-Toluidine Structure

Detail

4'-Methylacetanilide Structure

4'-Methylacetanilide

~%

PYRROLIDINE, 1-(4-METHYLPHENYL)- Structure

PYRROLIDINE, 1-...

n,n-diethyl-p-toluidine Structure

n,n-diethyl-p-t...

p-Toluidine Structure

Detail

4-Chloroacetanilide Structure

4-Chloroacetanilide

~%

N-(4-chlorophenyl)-N,N-diethylamine Structure

N-(4-chlorophen...

N-(4-chlorophenyl)-N-ethylacetamide Structure

N-(4-chlorophen...

4-Chloroaniline Structure

4-Chloroaniline

Detail

N-METHYLACETANILIDE Structure

N-METHYLACETANILIDE

~%

N-ETHYL-N-METHYLANILINE Structure

N-ETHYL-N-METHY...

N,N-Dimethylaniline Structure

N,N-Dimethylaniline

n-benzylacetamide Structure

n-benzylacetamide

~%

N-ethyldibenzylamine Structure

N-ethyldibenzylamine

benzyldiethylamine Structure

benzyldiethylamine

Tribenzylamine Structure

Detail

Benzylamine Structure

~%

N-ethyldibenzylamine Structure

N-ethyldibenzylamine

Tribenzylamine Structure

N-Ethylbenzylamine Structure

N-Ethylbenzylamine

Detail

Benzanilide Structure

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

N/A Structure

Benzylideneaniline Structure

Benzylideneaniline

Benzanilide Structure

Structure

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

N/A Structure

N-Benzoyldiphenylamine Structure

N-Benzoyldiphen...

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

Benzenemethanamine, N,N-diphenyl- Structure

Benzenemethanam...

Diphenylamine Structure

Detail

N-phenylnonanamide Structure

N-phenylnonanamide

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

N/A Structure

Acetanilide Structure

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

N/A Structure

Acetamide,N,N-diphenyl- Structure

Acetamide,N,N-d...

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

Benzenemethanamine, N,N-diphenyl- Structure

Benzenemethanam...

Benzoyl chloride Structure

Benzoyl chloride

Diphenylamine Structure

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

Benzenemethanamine, N,N-diphenyl- Structure

Benzenemethanam...

N-METHYLACETANILIDE Structure

N-METHYLACETANILIDE

~%

N-ETHYL-N-METHYLANILINE Structure

N-ETHYL-N-METHY...

N,N-Dimethylaniline Structure

N,N-Dimethylaniline

1N1&VR Structure

~%

dimethylbenzylamine Structure

dimethylbenzylamine

dibemethine Structure

Tribenzylamine Structure

Detail

Benzenecarboximidic acid, N-methyl- (9CI) Structure

Benzenecarboxim...

~%

dimethylbenzylamine Structure

dimethylbenzylamine

dibemethine Structure

Tribenzylamine Structure

Detail

Benzanilide Structure

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

N/A Structure

Benzylideneaniline Structure

Benzylideneaniline

Acetamide,N,N-diphenyl- Structure

Acetamide,N,N-d...

~%

Diphenylamine Structure

N,N-Diethylaniline Structure

N,N-Diethylaniline

N-ethyl-N-phenylbenzenamine Structure

N-ethyl-N-pheny...

N-Benzoyldiphenylamine Structure

N-Benzoyldiphen...

~%

Benzenemethanamine,N-phenyl-N-(phenylmethyl)- Structure

Benzenemethanam...

Benzenemethanamine, N,N-diphenyl- Structure

Benzenemethanam...

Diphenylamine Structure

Detail

3'-Methylacetanilide Structure

3'-Methylacetanilide

~%

PYRROLIDINE, 1-(3-METHYLPHENYL)- Structure

PYRROLIDINE, 1-...

3-Toluidine Structure

N-Ethyl-3-methylaniline Structure

N-Ethyl-3-methy...

Detail

2'-Chloroacetanilide Structure

2'-Chloroacetanilide

~%

2-Chloroaniline Structure

2-Chloroaniline

n-benzylacetamide Structure

n-benzylacetamide

~%

N-ethyldibenzylamine Structure

N-ethyldibenzylamine

benzyldiethylamine Structure

benzyldiethylamine

Tribenzylamine Structure

Detail

Acetanilide Structure

~%

N-Ethylaniline Structure

N,N-Diethylaniline Structure

N,N-Diethylaniline

Acetanilide Structure

~%

Ethanol Structure

N-Ethylaniline Structure

N,N-Diethylaniline Structure

N,N-Diethylaniline

Acetanilide Structure

~%

N-Ethylaniline Structure

Structure

N,N-Diethylaniline Structure

N,N-Diethylaniline

Acetamide,N,N-diphenyl- Structure

Acetamide,N,N-d...

~%

Diphenylamine Structure

N,N-Diethylaniline Structure

N,N-Diethylaniline

N-ethyl-N-phenylbenzenamine Structure

N-ethyl-N-pheny...

Reductive monoalkylation of aromatic and aliphatic nitro com...

[Nacario, Ruel; Kotakonda, Shailaja; Fouchard, David M. D.; Tillekeratne, L. M. Viranga; Hudson, Richard A. Organic Letters, 2005 , vol. 7, # 3 p. 471 - 474]

Reductive monoalkylation of aromatic and aliphatic nitro com...

[Nacario, Ruel; Kotakonda, Shailaja; Fouchard, David M. D.; Tillekeratne, L. M. Viranga; Hudson, Richard A. Organic Letters, 2005 , vol. 7, # 3 p. 471 - 474]

The Mechanism of Dye Formation in Color Photography. VII. In...

[Journal of the American Chemical Society, , vol. 82, p. 1988 - 1996]

One-pot reductive amination of acetals with aromatic amines ...

[Park, Eun Soo; Lee, Ji Hee; Kim, Soo Jung; Yoon, Cheol Min Synthetic Communications, 2003 , vol. 33, # 19 p. 3387 - 3396]

The rapid synthesis of organic compounds in microwave ovens

[Jiang, Yu-Lin; Hu, Yu-Qiao; Feng, Shu-Qing; Wu, Ji-Shan; Wu, Zu-Wang; Yuan, Yun-Cheng; Liu, Jun-Min; Hao, Qing-Sheng; Li, De-Peng Synthetic Communications, 1996 , vol. 26, # 1 p. 161 - 164]